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Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites
BACKGROUND: African Americans (AAs) experience premature chronic health outcomes and longevity disparities consistent with an accelerated aging phenotype. DNA methylation (DNAm) levels at specific CpG positions are hallmarks of aging evidenced by the presence of age-associated differentially methyla...
Autores principales: | Tajuddin, Salman M., Hernandez, Dena G., Chen, Brian H., Noren Hooten, Nicole, Mode, Nicolle A., Nalls, Mike A., Singleton, Andrew B., Ejiogu, Ngozi, Chitrala, Kumaraswamy Naidu, Zonderman, Alan B., Evans, Michele K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700815/ https://www.ncbi.nlm.nih.gov/pubmed/31426852 http://dx.doi.org/10.1186/s13148-019-0722-1 |
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