Parkin gene mutations are not common, but its epigenetic inactivation is a frequent event and predicts poor survival in advanced breast cancer patients

BACKGROUND: Progression of breast cancer involves both genetic and epigenetic factors. Parkin gene has been identified as a tumor suppressor gene in the pathogenesis of various cancers. Nevertheless, the putative role of Parkin in breast cancer remains largely unknown. Therefore, we evaluated the re...

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Detalles Bibliográficos
Autores principales: Wahabi, Khushnuma, Perwez, Ahmad, Kamarudheen, Shabeena, Bhat, Zafar Iqbal, Mehta, Anurag, Rizvi, M. Moshahid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700819/
https://www.ncbi.nlm.nih.gov/pubmed/31429726
http://dx.doi.org/10.1186/s12885-019-6013-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700819/
https://www.ncbi.nlm.nih.gov/pubmed/31429726
http://dx.doi.org/10.1186/s12885-019-6013-6

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