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Microglial P2Y12 receptor regulates ventral hippocampal CA1 neuronal excitability and innate fear in mice
The P2Y12 receptor (P2Y12R) is a purinoceptor that is selectively expressed in microglia in the central nervous system. As a signature receptor, microglial P2Y12R mediates process chemotaxis towards ADP/ATP gradients and is engaged in several neurological diseases including chronic pain, stroke and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700820/ https://www.ncbi.nlm.nih.gov/pubmed/31426845 http://dx.doi.org/10.1186/s13041-019-0492-x |