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Microglial P2Y12 receptor regulates ventral hippocampal CA1 neuronal excitability and innate fear in mice

The P2Y12 receptor (P2Y12R) is a purinoceptor that is selectively expressed in microglia in the central nervous system. As a signature receptor, microglial P2Y12R mediates process chemotaxis towards ADP/ATP gradients and is engaged in several neurological diseases including chronic pain, stroke and...

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Detalles Bibliográficos
Autores principales: Peng, Jiyun, Liu, Yong, Umpierre, Anthony D., Xie, Manling, Tian, Dai-Shi, Richardson, Jason R., Wu, Long-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700820/
https://www.ncbi.nlm.nih.gov/pubmed/31426845
http://dx.doi.org/10.1186/s13041-019-0492-x