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Estrogen inhibits autophagy and promotes growth of endometrial cancer by promoting glutamine metabolism

BACKGROUND: Excessive estrogen exposure is an important pathogenic factor in uterine endometrial cancer (UEC). Recent studies have reported the metabolic properties can influence the progression of UEC. However, the underlying mechanisms have not been fully elucidated. METHODS: Glutaminase (GLS), MY...

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Detalles Bibliográficos
Autores principales: Zhou, Wen-Jie, Zhang, Jie, Yang, Hui-Li, Wu, Ke, Xie, Feng, Wu, Jiang-Nan, Wang, Yan, Yao, Li, Zhuang, Yan, Xiang, Jiang-Dong, Zhang, Ai-Jun, He, Yin-Yan, Li, Ming-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700828/
https://www.ncbi.nlm.nih.gov/pubmed/31429768
http://dx.doi.org/10.1186/s12964-019-0412-9