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The different expression of caspase-1 in HBV-related liver disease and acts as a biomarker for acute-on-chronic liver failure

BACKGROUND: Caspase-1 is an evolutionarily conserved enzyme that proteolytically cleaves the precursors of the inflammatory cytokines interleukin 1β and interleukin 18. However, the role of caspase-1 in determining the severity of acute-on-chronic liver failure (ACLF) has yet to be elucidated. We ev...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangying, Dong, Peiling, Xu, Lin, Tian, Yuan, Sun, Huayin, Shi, Hongbo, Duan, Zhongping, Chen, Liyan, Ren, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700995/
https://www.ncbi.nlm.nih.gov/pubmed/31429707
http://dx.doi.org/10.1186/s12876-019-1064-3