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A novel CD147 inhibitor, SP-8356, reduces neointimal hyperplasia and arterial stiffness in a rat model of partial carotid artery ligation

BACKGROUND: Neointimal hyperplasia and its related arterial stiffness are the crucial pathophysiological features in atherosclerosis and in-stent restenosis. Cluster of differentiation 147 (CD147), a member of the immunoglobulin super family that induces the expression of matrix metalloproteinase-9...

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Detalles Bibliográficos
Autores principales: Pahk, Kisoo, Noh, Hyojin, Joung, Chanmin, Jang, Mi, Song, Hwa Young, Kim, Kyung Won, Han, Kihoon, Hwang, Jong-Ik, Kim, Sungeun, Kim, Won-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700999/
https://www.ncbi.nlm.nih.gov/pubmed/31429778
http://dx.doi.org/10.1186/s12967-019-2024-y