NFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium

BACKGROUND: How high-salt intake leads to the occurrence of many cardiovascular diseases such as atherosclerosis is a fundamental question in pathology. Here we postulated that high-salt-induced NFAT5 controls the inflammasome activation by directly regulating NLRP3, which mediates the expression of...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Pingping, Zha, Shenfang, Shen, Xinkun, Zhao, Yulan, Li, Li, Yang, Li, Lei, Mingxing, Liu, Wanqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701070/
https://www.ncbi.nlm.nih.gov/pubmed/31429763
http://dx.doi.org/10.1186/s12964-019-0406-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701070/
https://www.ncbi.nlm.nih.gov/pubmed/31429763
http://dx.doi.org/10.1186/s12964-019-0406-7

Ejemplares similares