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A Novel Role for Triglyceride Metabolism in Foxp3 Expression

Lipid metabolism plays a key role in many cellular processes. We show here that regulatory T cells have enhanced lipid storage within subcellular lipid droplets (LD). They also express elevated amounts of both isoforms of diacylglycerol acyl transferase (DGAT1 & 2), enzymes required for the term...

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Detalles Bibliográficos
Autores principales: Howie, Duncan, Ten Bokum, Annemieke, Cobbold, Stephen Paul, Yu, Zhanru, Kessler, Benedikt M., Waldmann, Herman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701200/
https://www.ncbi.nlm.nih.gov/pubmed/31456800
http://dx.doi.org/10.3389/fimmu.2019.01860