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A Novel Role for Triglyceride Metabolism in Foxp3 Expression
Lipid metabolism plays a key role in many cellular processes. We show here that regulatory T cells have enhanced lipid storage within subcellular lipid droplets (LD). They also express elevated amounts of both isoforms of diacylglycerol acyl transferase (DGAT1 & 2), enzymes required for the term...
Autores principales: | Howie, Duncan, Ten Bokum, Annemieke, Cobbold, Stephen Paul, Yu, Zhanru, Kessler, Benedikt M., Waldmann, Herman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701200/ https://www.ncbi.nlm.nih.gov/pubmed/31456800 http://dx.doi.org/10.3389/fimmu.2019.01860 |
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