Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis

Hippocampal neuron death is a key factor in vascular dementia (VD) induced by chronic cerebral hypoperfusion (CCH). Dl-3-n-butylphthalide (NBP) is a multiple-effects drug. Therefore, the potential molecular mechanisms underlying CCH and its feasible treatment should be investigated. This study had t...

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Detalles Bibliográficos
Autores principales: Li, Wenxian, Wei, Di, Lin, Jiaxing, Liang, Jianye, Xie, Xiaomei, Song, Kangping, Huang, Li’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701226/
https://www.ncbi.nlm.nih.gov/pubmed/31456664
http://dx.doi.org/10.3389/fncel.2019.00351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701226/
https://www.ncbi.nlm.nih.gov/pubmed/31456664
http://dx.doi.org/10.3389/fncel.2019.00351

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