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Early Treatment with Empagliflozin and GABA Improves β-Cell Mass and Glucose Tolerance in Streptozotocin-Treated Mice

While the autoimmune character of T1D (type 1 diabetes) is being challenged, it is currently recognized that inflammation plays a key role in its development. We hypothesized that glucotoxicity could contribute to β-cell mass destruction through participation in islet inflammation. We evaluated the...

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Detalles Bibliográficos
Autores principales: Daems, Caroline, Welsch, Sophie, Boughaleb, Hasnae, Vanderroost, Juliette, Robert, Annie, Sokal, Etienne, Lysy, Philippe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701376/
https://www.ncbi.nlm.nih.gov/pubmed/31467926
http://dx.doi.org/10.1155/2019/2813489