Presenilin 1 Regulates [Ca(2+)]i and Mitochondria/ER Interaction in Cultured Rat Hippocampal Neurons

Mutations in the presenilin 1 (PS1) gene are a major trigger of familial Alzheimer's disease (AD), yet the mechanisms affected by mutated PS1 causing cognitive decline are not yet elucidated. In the present study, we compared rat hippocampal neurons in culture, transfected with PS1 or with muta...

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Detalles Bibliográficos
Autores principales: Korkotian, Eduard, Meshcheriakova, Anna, Segal, Menahem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701405/
https://www.ncbi.nlm.nih.gov/pubmed/31467635
http://dx.doi.org/10.1155/2019/7284967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701405/
https://www.ncbi.nlm.nih.gov/pubmed/31467635
http://dx.doi.org/10.1155/2019/7284967

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