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Fruquintinib: a novel antivascular endothelial growth factor receptor tyrosine kinase inhibitor for the treatment of metastatic colorectal cancer

Angiogenesis plays a critical role in the neoplastic growth, progression, and metastasis of colorectal cancer (CRC) in a process regulated by vascular endothelial growth factor (VEGF) family members and their receptors (VEGFR). Several small-molecule anti-VEGFR tyrosine kinase inhibitors (TKIs), suc...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Zou, Jia-Yun, Wang, Zhe, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701622/
https://www.ncbi.nlm.nih.gov/pubmed/31496821
http://dx.doi.org/10.2147/CMAR.S215533