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Influence of type-4 dipeptidyl peptidase inhibition on endothelium-dependent relaxation of aortae from a db/db mouse model of type 2 diabetes: a comparison with the effect of glimepiride

PURPOSE: The aim of this study was to investigate the effects of the type-4 dipeptidyl peptidase (DPP-4) inhibitors linagliptin and vildagliptin as well as the sulfonylurea glimepiride on endothelium-dependent relaxation of aortae from female db/db mice with established hyperglycemia to determine wh...

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Detalles Bibliográficos
Autores principales: Woodman, Owen L, Ortega, Jacinta M, Hart, Joanne L, Klein, Thomas, Potocnik, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701666/
https://www.ncbi.nlm.nih.gov/pubmed/31496778
http://dx.doi.org/10.2147/DMSO.S215086