Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in Lmna(H222P/H222P) mutant mice

Laminopathies are tissue-selective diseases that affect differently in organ systems. Mutations in nuclear envelopes, emerin (Emd) and lamin A/C (Lmna) genes, cause clinically indistinguishable myopathy called Emery-Dreifuss muscular dystrophy (EDMD) and limb-girdle muscular dystrophy. Several murin...

Descripción completa

Detalles Bibliográficos
Autores principales: Wada, Eiji, Kato, Megumi, Yamashita, Kaori, Kokuba, Hiroko, Liang, Wen-Chen, Bonne, Gisèle, Hayashi, Yukiko K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701770/
https://www.ncbi.nlm.nih.gov/pubmed/31430335
http://dx.doi.org/10.1371/journal.pone.0221512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701770/
https://www.ncbi.nlm.nih.gov/pubmed/31430335
http://dx.doi.org/10.1371/journal.pone.0221512

Ejemplares similares