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Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in Lmna(H222P/H222P) mutant mice
Laminopathies are tissue-selective diseases that affect differently in organ systems. Mutations in nuclear envelopes, emerin (Emd) and lamin A/C (Lmna) genes, cause clinically indistinguishable myopathy called Emery-Dreifuss muscular dystrophy (EDMD) and limb-girdle muscular dystrophy. Several murin...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701770/ https://www.ncbi.nlm.nih.gov/pubmed/31430335 http://dx.doi.org/10.1371/journal.pone.0221512 |