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Islets from human donors with higher but not lower hemoglobin A1c levels respond to gastrin treatment in vitro
Gastrin is a peptide hormone, which in combination with other factors such as TGFα, EGF or GLP-1, is capable of increasing beta cell mass and lowering blood glucose levels in adult diabetic mice. In humans, administration of a bolus of gastrin alone induces insulin secretion suggesting that gastrin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701795/ https://www.ncbi.nlm.nih.gov/pubmed/31430329 http://dx.doi.org/10.1371/journal.pone.0221456 |