Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence

A mucosal infectious disease episode can render the host either more or less susceptible to recurrent infection, but the specific mechanisms that tip the balance remain unclear. We investigated this question in a mouse model of recurrent urinary tract infection and found that a prior bladder infecti...

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Detalles Bibliográficos
Autores principales: Yu, Lu, O'Brien, Valerie P, Livny, Jonathan, Dorsey, Denise, Bandyopadhyay, Nirmalya, Colonna, Marco, Caparon, Michael G, Roberson, Elisha DO, Hultgren, Scott J, Hannan, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701943/
https://www.ncbi.nlm.nih.gov/pubmed/31429405
http://dx.doi.org/10.7554/eLife.46677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701943/
https://www.ncbi.nlm.nih.gov/pubmed/31429405
http://dx.doi.org/10.7554/eLife.46677

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