Programmable RNA N(6)-methyladenosine editing by CRISPR-Cas9 conjugates

RNA modification in the form of N(6)-methyladenosine (m(6)A) regulates nearly all the post-transcriptional processes. The asymmetric m(6)A deposition suggests that regional methylation may have distinct functional consequences. However, current RNA biology tools do not distinguish the contribution o...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Min, Zhou, Jun, Mao, Yuanhui, Ji, Quanquan, Qian, Shu-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702037/
https://www.ncbi.nlm.nih.gov/pubmed/31383972
http://dx.doi.org/10.1038/s41589-019-0327-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702037/
https://www.ncbi.nlm.nih.gov/pubmed/31383972
http://dx.doi.org/10.1038/s41589-019-0327-1

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