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Programmable RNA N(6)-methyladenosine editing by CRISPR-Cas9 conjugates
RNA modification in the form of N(6)-methyladenosine (m(6)A) regulates nearly all the post-transcriptional processes. The asymmetric m(6)A deposition suggests that regional methylation may have distinct functional consequences. However, current RNA biology tools do not distinguish the contribution o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702037/ https://www.ncbi.nlm.nih.gov/pubmed/31383972 http://dx.doi.org/10.1038/s41589-019-0327-1 |