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Early functional alterations in membrane properties and neuronal degeneration are hallmarks of progressive hearing loss in NOD mice

Presbycusis or age-related hearing loss (ARHL) is the most common sensory deficit in the human population. A substantial component of the etiology stems from pathological changes in sensory and non-sensory cells in the cochlea. Using a non-obese diabetic (NOD) mouse model, we have characterized chan...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Han, Park, Seojin, Perez-Flores, Maria C., Wang, Wenying, Kim, Hyo Jeong, Izu, Leighton, Gratton, Michael Anne, Chiamvimonvat, Nipavan, Yamoah, Ebenezer N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702171/
https://www.ncbi.nlm.nih.gov/pubmed/31431657
http://dx.doi.org/10.1038/s41598-019-48376-x