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Early functional alterations in membrane properties and neuronal degeneration are hallmarks of progressive hearing loss in NOD mice
Presbycusis or age-related hearing loss (ARHL) is the most common sensory deficit in the human population. A substantial component of the etiology stems from pathological changes in sensory and non-sensory cells in the cochlea. Using a non-obese diabetic (NOD) mouse model, we have characterized chan...
Autores principales: | Lee, Jeong Han, Park, Seojin, Perez-Flores, Maria C., Wang, Wenying, Kim, Hyo Jeong, Izu, Leighton, Gratton, Michael Anne, Chiamvimonvat, Nipavan, Yamoah, Ebenezer N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702171/ https://www.ncbi.nlm.nih.gov/pubmed/31431657 http://dx.doi.org/10.1038/s41598-019-48376-x |
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