MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner

MALT1 is a central signaling component in innate and adaptive immunity by regulating NF-κB and other key signaling pathways in different cell types. Activities of MALT1 are mediated by its scaffold and protease functions. Because of its role in lymphocyte activation and proliferation, inhibition of...

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Detalles Bibliográficos
Autores principales: Demeyer, Annelies, Skordos, Ioannis, Driege, Yasmine, Kreike, Marja, Hochepied, Tino, Baens, Mathijs, Staal, Jens, Beyaert, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702287/
https://www.ncbi.nlm.nih.gov/pubmed/31474984
http://dx.doi.org/10.3389/fimmu.2019.01898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702287/
https://www.ncbi.nlm.nih.gov/pubmed/31474984
http://dx.doi.org/10.3389/fimmu.2019.01898

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