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MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner
MALT1 is a central signaling component in innate and adaptive immunity by regulating NF-κB and other key signaling pathways in different cell types. Activities of MALT1 are mediated by its scaffold and protease functions. Because of its role in lymphocyte activation and proliferation, inhibition of...
Autores principales: | Demeyer, Annelies, Skordos, Ioannis, Driege, Yasmine, Kreike, Marja, Hochepied, Tino, Baens, Mathijs, Staal, Jens, Beyaert, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702287/ https://www.ncbi.nlm.nih.gov/pubmed/31474984 http://dx.doi.org/10.3389/fimmu.2019.01898 |
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