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Changes in Neuroimmune and Neuronal Death Markers after Adolescent Alcohol Exposure in Rats are Reversed by Donepezil

Adolescent intermittent ethanol (AIE) exposure diminishes neurogenesis and dendritic spine density in the dentate gyrus. The cholinesterase inhibitor, donepezil (Aricept), reverses AIE effects on dendritic spines, possibly by interacting with inflammatory and/or epigenetic mediators after AIE exposu...

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Detalles Bibliográficos
Autores principales: Swartzwelder, H. S., Healey, Kati L., Liu, Wen, Dubester, Kira, Miller, Kelsey M., Crews, Fulton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702347/
https://www.ncbi.nlm.nih.gov/pubmed/31431637
http://dx.doi.org/10.1038/s41598-019-47039-1