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Development of multifunctional Overhauser-enhanced magnetic resonance imaging for concurrent in vivo mapping of tumor interstitial oxygenation, acidosis and inorganic phosphate concentration

Tumor oxygenation (pO(2)), acidosis (pH) and interstitial inorganic phosphate concentration (Pi) are important parameters of the malignant behavior of cancer. A noninvasive procedure that enables visualization of these parameters may provide unique information about mechanisms of tumor pathophysiolo...

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Detalles Bibliográficos
Autores principales: Gorodetskii, Artem A., Eubank, Timothy D., Driesschaert, Benoit, Poncelet, Martin, Ellis, Emily, Khramtsov, Valery V., Bobko, Andrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702349/
https://www.ncbi.nlm.nih.gov/pubmed/31431629
http://dx.doi.org/10.1038/s41598-019-48524-3