Chimeric hepatitis B virus core particles displaying Neisserial surface protein A confer protection against virulent Neisseria meningitidis serogroup B in BALB/c mice

PURPOSE: The primary goal of the present study was to explore and evaluate the highly conserved Neisserial surface protein A (NspA) molecule, fused with truncated HBV virus-like particles (VLPs), as a candidate vaccine against the virulent Neisseria meningitidis serogroup B (NMB). METHODS: NspA was...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, YongLi, Yan, Ting, Cao, Hui, Liu, Peng, Zheng, Kang, Li, Zhenyu, Deng, Qing, Hu, SiHai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702424/
https://www.ncbi.nlm.nih.gov/pubmed/31496701
http://dx.doi.org/10.2147/IJN.S206210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702424/
https://www.ncbi.nlm.nih.gov/pubmed/31496701
http://dx.doi.org/10.2147/IJN.S206210

Ejemplares similares