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Chimeric hepatitis B virus core particles displaying Neisserial surface protein A confer protection against virulent Neisseria meningitidis serogroup B in BALB/c mice
PURPOSE: The primary goal of the present study was to explore and evaluate the highly conserved Neisserial surface protein A (NspA) molecule, fused with truncated HBV virus-like particles (VLPs), as a candidate vaccine against the virulent Neisseria meningitidis serogroup B (NMB). METHODS: NspA was...
Autores principales: | Hou, YongLi, Yan, Ting, Cao, Hui, Liu, Peng, Zheng, Kang, Li, Zhenyu, Deng, Qing, Hu, SiHai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702424/ https://www.ncbi.nlm.nih.gov/pubmed/31496701 http://dx.doi.org/10.2147/IJN.S206210 |
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