Unraveling the molecular principles by which ceramides commit cells to death

Ceramides are central intermediates of sphingolipid metabolism that can activate a variety of tumor suppressive cellular programs, including cell cycle arrest, senescence and apoptosis. Indeed, perturbations in ceramide generation and turnover are frequently linked to cancer cell survival and resist...

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Detalles Bibliográficos
Autores principales: Dadsena, Shashank, Hassan, Dina G., Holthuis, Joost C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2019
Materias:
Microreview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702447/
https://www.ncbi.nlm.nih.gov/pubmed/31440742
http://dx.doi.org/10.15698/cst2019.08.196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702447/
https://www.ncbi.nlm.nih.gov/pubmed/31440742
http://dx.doi.org/10.15698/cst2019.08.196

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