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Unraveling the molecular principles by which ceramides commit cells to death
Ceramides are central intermediates of sphingolipid metabolism that can activate a variety of tumor suppressive cellular programs, including cell cycle arrest, senescence and apoptosis. Indeed, perturbations in ceramide generation and turnover are frequently linked to cancer cell survival and resist...
Autores principales: | Dadsena, Shashank, Hassan, Dina G., Holthuis, Joost C.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702447/ https://www.ncbi.nlm.nih.gov/pubmed/31440742 http://dx.doi.org/10.15698/cst2019.08.196 |
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