The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function

Transcription factors positively and/or negatively impact gene expression by recruiting coregulatory factors, which interact through protein-protein binding. Here we demonstrate that mouse pancreas size and islet β-cell function are controlled by the ATP-dependent Swi/Snf chromatin remodeling coregu...

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Detalles Bibliográficos
Autores principales: Spaeth, Jason M., Liu, Jin-Hua, Peters, Daniel, Guo, Min, Osipovich, Anna B., Mohammadi, Fardin, Roy, Nilotpal, Bhushan, Anil, Magnuson, Mark A., Hebrok, Matthias, Wright, Christopher V.E., Stein, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702633/
https://www.ncbi.nlm.nih.gov/pubmed/31201281
http://dx.doi.org/10.2337/db19-0349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702633/
https://www.ncbi.nlm.nih.gov/pubmed/31201281
http://dx.doi.org/10.2337/db19-0349

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