Cargando…

The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function

Transcription factors positively and/or negatively impact gene expression by recruiting coregulatory factors, which interact through protein-protein binding. Here we demonstrate that mouse pancreas size and islet β-cell function are controlled by the ATP-dependent Swi/Snf chromatin remodeling coregu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spaeth, Jason M., Liu, Jin-Hua, Peters, Daniel, Guo, Min, Osipovich, Anna B., Mohammadi, Fardin, Roy, Nilotpal, Bhushan, Anil, Magnuson, Mark A., Hebrok, Matthias, Wright, Christopher V.E., Stein, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2019
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702633/ https://www.ncbi.nlm.nih.gov/pubmed/31201281 http://dx.doi.org/10.2337/db19-0349

Ejemplares similares

Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning
por: Spaeth, Jason M., et al.
Publicado: (2017)

Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells Into β-Cells In Vivo
por: Matsuoka, Taka-aki, et al.
Publicado: (2017)

Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome
por: Wagner, Felix R., et al.
Publicado: (2020)

SWI/SNF remains localized to chromatin in the presence of SCHLAP1
por: Raab, Jesse R., et al.
Publicado: (2018)

Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
por: Menon, Debashish U., et al.
Publicado: (2021)

Architecture of SWI/SNF chromatin remodeling complex
por: Zhang, Zhihui, et al.
Publicado: (2018)

SWI/SNF Chromatin Remodeling Enzymes in Melanoma
por: Dreier, Megan R., et al.
Publicado: (2022)

Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells
por: Osipovich, Anna B., et al.
Publicado: (2020)

The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth
por: Hang, Yan, et al.
Publicado: (2014)

Generation of Remosomes by the SWI/SNF Chromatin Remodeler Family
por: Shukla, Manu Shubhdarshan, et al.
Publicado: (2019)

Chromatin remodeling (SWI/SNF) complexes, cancer, and response to immunotherapy
por: Krishnamurthy, Nithya, et al.
Publicado: (2022)

Islet α-, β-, and δ-Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor
por: Hunter, Chad S., et al.
Publicado: (2013)

Role of BH3-Only Molecules Bim and Puma in β-Cell Death in Pdx1 Deficiency
por: Ren, Decheng, et al.
Publicado: (2014)

Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion
por: Golson, Maria L., et al.
Publicado: (2015)

Maturation of Human Embryonic Stem Cell–Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice
por: Rezania, Alireza, et al.
Publicado: (2012)

Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity
por: He, Zhenyu, et al.
Publicado: (2021)

Islet-1 Is Essential for Pancreatic β-Cell Function
por: Ediger, Benjamin N., et al.
Publicado: (2014)

Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca(2+)-Regulated Genes
por: Stancill, Jennifer S., et al.
Publicado: (2017)

The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer
por: Wu, Qiong, et al.
Publicado: (2017)

SWI/SNF Infobase—An exclusive information portal for SWI/SNF remodeling complex subunits
por: Mani, Udayakumar, et al.
Publicado: (2017)

SWI/SNF Chromatin-remodeling Factors: Multiscale Analyses and Diverse Functions
por: Euskirchen, Ghia, et al.
Publicado: (2012)

Chromatin Remodeling BAF (SWI/SNF) Complexes in Neural Development and Disorders
por: Sokpor, Godwin, et al.
Publicado: (2017)

Cryo-EM structure of SWI/SNF chromatin remodeling complex with nucleosome
por: Han, Yan, et al.
Publicado: (2020)

The role of the SWI/SNF chromatin remodeling complex in pancreatic ductal adenocarcinoma
por: Tsuda, Motoyuki, et al.
Publicado: (2020)

Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy
por: Wanior, Marek, et al.
Publicado: (2021)

Swi/Snf Chromatin Remodeling Regulates Transcriptional Interference and Gene Repression
por: Morse, Kaitlin, et al.
Publicado: (2023)

Intracutaneous Transplantation of Islets Within a Biodegradable Temporizing Matrix as an Alternative Site for Islet Transplantation
por: Rojas-Canales, Darling, et al.
Publicado: (2023)

A Role for von Hippel-Lindau Protein in Pancreatic β-Cell Function
por: Puri, Sapna, et al.
Publicado: (2009)

Somatostatin Secreted by Islet δ-Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function
por: Hauge-Evans, Astrid C., et al.
Publicado: (2009)

Formation of Composite Endothelial Cell–Mesenchymal Stem Cell Islets: A Novel Approach to Promote Islet Revascularization
por: Johansson, Ulrika, et al.
Publicado: (2008)

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes
por: Raab, Jesse R., et al.
Publicado: (2015)

Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells
por: Banerjee, Ronadip R., et al.
Publicado: (2016)

Human SWI/SNF directs sequence-specific chromatin changes on promoter polynucleosomes
por: Sims, Hillel I., et al.
Publicado: (2008)

Regulation of Mec1 kinase activity by the SWI/SNF chromatin remodeling complex
por: Kapoor, Prabodh, et al.
Publicado: (2015)

The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
por: Alver, Burak H., et al.
Publicado: (2017)

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex
por: Lindén, Malin, et al.
Publicado: (2019)

New alleles of the SWI/SNF chromatin remodeling complex gene phf-10
por: Mathies, Laura D, et al.
Publicado: (2022)

Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler
por: Woodley, Chase M., et al.
Publicado: (2021)

Distinct roles for RSC and SWI/SNF chromatin remodelers in genomic excision repair
por: Bohm, Kaitlynne A., et al.
Publicado: (2021)

Landscape of mSWI/SNF chromatin remodeling complex perturbations in neurodevelopmental disorders
por: Valencia, Alfredo M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ij6niptjnobtm5948aq5si1gdp