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Accelerated and Severe Lupus Nephritis Benefits From M1, an Active Metabolite of Ginsenoside, by Regulating NLRP3 Inflammasome and T Cell Functions in Mice

Chinese herbal medicines used in combination have long-term been shown to be mild remedies with “integrated effects.” However, our study provides the first demonstration that M1, an active metabolite of ginsenoside, exerted its dramatic therapeutic effects on accelerated and severe lupus nephritis (...

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Detalles Bibliográficos
Autores principales: Lin, Tsai-Jung, Wu, Chung-Yao, Tsai, Pei-Yi, Hsu, Wan-Han, Hua, Kuo-Feng, Chu, Ching-Liang, Lee, Yu-Chieh, Chen, Ann, Lee, Sheau-Long, Lin, Yi-Jin, Hsieh, Chih-Yu, Yang, Shin-Ruen, Liu, Feng-Cheng, Ka, Shuk-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702666/
https://www.ncbi.nlm.nih.gov/pubmed/31475012
http://dx.doi.org/10.3389/fimmu.2019.01951