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Abrogation of lysophosphatidic acid receptor 1 ameliorates murine vasculitis

BACKGROUND: Lysophosphatidic acid (LPA), generated by autotaxin (ATX), is a bioactive lipid mediator that binds to the receptors (LPA(1–6)), and serves as an important mediator in inflammation. Previous studies have demonstrated that LPA-LPA(1) cascade contributes to arthritis and skin sclerosis. In...

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Detalles Bibliográficos
Autores principales:	Miyabe, Chie, Miyabe, Yoshishige, Nagai, Jun, Miura, Noriko N., Ohno, Naohito, Chun, Jerold, Tsuboi, Ryoji, Ueda, Hiroshi, Miyasaka, Masayuki, Miyasaka, Nobuyuki, Nanki, Toshihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702724/ https://www.ncbi.nlm.nih.gov/pubmed/31429784 http://dx.doi.org/10.1186/s13075-019-1973-0

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