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The DNA repair protein SHPRH is a nucleosome-stimulated ATPase and a nucleosome-E3 ubiquitin ligase

BACKGROUND: Maintenance of genome integrity during DNA replication is crucial to the perpetuation of all organisms. In eukaryotes, the bypass of DNA lesions by the replication machinery prevents prolonged stalling of the replication fork, which could otherwise lead to greater damages such as gross c...

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Detalles Bibliográficos
Autores principales: Brühl, Joanna, Trautwein, Jonathan, Schäfer, Agnes, Linne, Uwe, Bouazoune, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702750/
https://www.ncbi.nlm.nih.gov/pubmed/31434570
http://dx.doi.org/10.1186/s13072-019-0294-5