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Inducible Gene Switches with Memory in Human T Cells for Cellular Immunotherapy
[Image: see text] Cell-based therapies that employ engineered T cells—including those modified to express chimeric antigen receptors (CARs)—to target cancer cells have demonstrated promising responses in clinical trials. However, engineered T cell responses must be regulated to prevent severe side e...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703182/ https://www.ncbi.nlm.nih.gov/pubmed/31268301 http://dx.doi.org/10.1021/acssynbio.8b00512 |