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Interplay of LIS1 and MeCP2: Interactions and Implications With the Neurodevelopmental Disorders Lissencephaly and Rett Syndrome

LIS1 is the main causative gene for lissencephaly, while MeCP2 is the main causative gene for Rett syndrome, both of which are neurodevelopmental diseases. Here we report nuclear functions for LIS1 and identify previously unrecognized physical and genetic interactions between the products of these t...

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Detalles Bibliográficos
Autores principales: Keidar, Liraz, Gerlitz, Gabi, Kshirsagar, Aditya, Tsoory, Michael, Olender, Tsviya, Wang, Xing, Yang, Ying, Chen, Yu-Sheng, Yang, Yun-Gui, Voineagu, Irina, Reiner, Orly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703185/
https://www.ncbi.nlm.nih.gov/pubmed/31474834
http://dx.doi.org/10.3389/fncel.2019.00370