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Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation

Enteropathogenic Escherichia coli and enterohemorrhagic E. coli (EPEC and EHEC, respectively) are extracellular pathogens that reorganize the host cell cytoskeleton to form “actin pedestals” beneath the tightly adherent bacteria, a critical step in pathogenesis. EPEC and EHEC inject effector protein...

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Detalles Bibliográficos
Autores principales: Singh, Vikash, Davidson, Anthony, Hume, Peter J., Koronakis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703428/
https://www.ncbi.nlm.nih.gov/pubmed/31431554
http://dx.doi.org/10.1128/mBio.01876-19