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mGluR5/ERK signaling regulated the phosphorylation and function of glycine receptor α1(ins) subunit in spinal dorsal horn of mice
Inhibitory glycinergic transmission in adult spinal cord is primarily mediated by glycine receptors (GlyRs) containing the α1 subunit. Here, we found that α1(ins), a longer α1 variant with 8 amino acids inserted into the intracellular large loop (IL) between transmembrane (TM)3 and TM4 domains, was...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703679/ https://www.ncbi.nlm.nih.gov/pubmed/31433808 http://dx.doi.org/10.1371/journal.pbio.3000371 |