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Wound-induced polyploidization is driven by Myc and supports tissue repair in the presence of DNA damage
Tissue repair usually requires either polyploid cell growth or cell division, but the molecular mechanism promoting polyploidy and limiting cell division remains poorly understood. Here, we find that injury to the adult Drosophila epithelium causes cells to enter the endocycle through the activation...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703715/ https://www.ncbi.nlm.nih.gov/pubmed/31315896 http://dx.doi.org/10.1242/dev.173005 |