TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections

In mice, neonatally-developing, self-reactive B-1 cells generate steady levels of natural antibodies throughout life. B-1 cells can, however, also rapidly respond to infections with increased local antibody production. The mechanisms regulating these two seemingly very distinct functions are poorly...

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Detalles Bibliográficos
Autores principales: Savage, Hannah P, Kläsener, Kathrin, Smith, Fauna L, Luo, Zheng, Reth, Michael, Baumgarth, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703853/
https://www.ncbi.nlm.nih.gov/pubmed/31433296
http://dx.doi.org/10.7554/eLife.46997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703853/
https://www.ncbi.nlm.nih.gov/pubmed/31433296
http://dx.doi.org/10.7554/eLife.46997

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