B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota

B-1a cells play an important role in mediating tissue homeostasis and protecting against infections. They are the main producers of ‘natural’ IgM, spontaneously secreted serum antibodies predominately reactive to self antigens, like phosphatidylcholine (PtC), or antigens expressed by the intestinal...

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Detalles Bibliográficos
Autores principales: Kreuk, Lieselotte SM, Koch, Meghan A, Slayden, Leianna C, Lind, Nicholas A, Chu, Sophia, Savage, Hannah P, Kantor, Aaron B, Baumgarth, Nicole, Barton, Gregory M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703855/
https://www.ncbi.nlm.nih.gov/pubmed/31433298
http://dx.doi.org/10.7554/eLife.47015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703855/
https://www.ncbi.nlm.nih.gov/pubmed/31433298
http://dx.doi.org/10.7554/eLife.47015

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