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Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss
Adenosine and its receptors play a key role in bone homeostasis and regeneration. Extracellular adenosine is generated from CD39 and CD73 activity in the cell membrane, through conversion of adenosine triphosphate to adenosine monophosphate (AMP) and AMP to adenosine, respectively. Despite the relev...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703860/ https://www.ncbi.nlm.nih.gov/pubmed/31457100 http://dx.doi.org/10.1126/sciadv.aax1387 |