Cargando…

Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss

Adenosine and its receptors play a key role in bone homeostasis and regeneration. Extracellular adenosine is generated from CD39 and CD73 activity in the cell membrane, through conversion of adenosine triphosphate to adenosine monophosphate (AMP) and AMP to adenosine, respectively. Despite the relev...

Descripción completa

Detalles Bibliográficos
Autores principales: Shih, Yu-Ru V., Liu, Mengqian, Kwon, Seong Keun, Iida, Masayuki, Gong, Ya, Sangaj, Nivedita, Varghese, Shyni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703860/
https://www.ncbi.nlm.nih.gov/pubmed/31457100
http://dx.doi.org/10.1126/sciadv.aax1387