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A prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells

Development of safe and efficient nanoscale vehicles that can deliver large molecular cargos into human cells could transform future human therapies and personalized medicine. Here, we design a hybrid viral vector composed of a prokaryotic virus (bacteriophage T4) and a eukaryotic virus [adeno-assoc...

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Detalles Bibliográficos
Autores principales: Zhu, Jingen, Tao, Pan, Mahalingam, Marthandan, Sha, Jian, Kilgore, Paul, Chopra, Ashok K., Rao, Venigalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703872/
https://www.ncbi.nlm.nih.gov/pubmed/31457098
http://dx.doi.org/10.1126/sciadv.aax0064