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Effect of Relaxin Expression from an Alginate Gel-Encapsulated Adenovirus on Scar Remodeling in a Pig Model

PURPOSE: Relaxin (RLX) is a transforming growth factor-β1 (TGF-β1) antagonist that is believed to function as a potent collagen re-arranger and a major suppressor of extracellular matrix components. Adenoviruses (Ads) are accepted vectors for cancer gene therapy. However, repeated treatments of Ad a...

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Detalles Bibliográficos
Autores principales: Yun, In Sik, Kang, Eunhye, Ahn, Hyo Min, Kim, Yong Oock, Rah, Dong Kyun, Roh, Tai Suk, Lee, Won Jai, Yun, Chae-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704020/
https://www.ncbi.nlm.nih.gov/pubmed/31433583
http://dx.doi.org/10.3349/ymj.2019.60.9.854