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Structural basis for lamin assembly at the molecular level

Nuclear structure and function are governed by lamins, which are intermediate filaments that mostly consist of α-helices. Different lamin assembly models have been proposed based on low resolution and fragmented structures. However, their assembly mechanisms are still poorly understood at the molecu...

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Detalles Bibliográficos
Autores principales: Ahn, Jinsook, Jo, Inseong, Kang, So-mi, Hong, Seokho, Kim, Suhyeon, Jeong, Soyeon, Kim, Yong-Hak, Park, Bum-Joon, Ha, Nam-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704074/
https://www.ncbi.nlm.nih.gov/pubmed/31434876
http://dx.doi.org/10.1038/s41467-019-11684-x