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Isosteviol Sodium Protects against Ischemic Stroke by Modulating Microglia/Macrophage Polarization via Disruption of GAS5/miR-146a-5p sponge

Recent studies have shown that transforming microglia phenotype from pro-inflammation of M1 phenotype to anti-inflammation and tissue-repairing M2 phenotype may be an effective therapeutic strategy for preventing ischemic stroke brain injury. Isosteviol Sodium (STV-Na) has shown promise as a neuropr...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Lu, Minyi, Zhang, Xiaofeng, Kuai, Yihe, Mei, Ying, Tan, Qiwen, Zhong, Kailun, Sun, Xiaoou, Tan, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704123/
https://www.ncbi.nlm.nih.gov/pubmed/31434993
http://dx.doi.org/10.1038/s41598-019-48759-0