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Extracorporeal shock waves protect cardiomyocytes from doxorubicin-induced cardiomyopathy by upregulating survivin via the integrin-ILK-Akt-Sp1/p53 axis

Doxorubicin (DOX) is a widely used anti-cancer drug; however, it has limited application due to cardiotoxicity. Extracorporeal shock waves (ESW) have been suggested to treat inflammatory and ischemic diseases, but the concrete effect of ESW in DOX-induced cardiomyopathy remain obscure. After H9c2 ce...

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Detalles Bibliográficos
Autores principales: Yoon Lee, Ji, Chung, Jihwa, Hwa Kim, Kyoung, Hyun An, Shung, Yi, Jeong-Eun, Ae Kwon, Kyoung, Kwon, Kihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704172/
https://www.ncbi.nlm.nih.gov/pubmed/31434946
http://dx.doi.org/10.1038/s41598-019-48470-0