The Use of Murine Models for Studying Mechanistic Insights of Genomic Instability in Multiple Myeloma

Multiple myeloma (MM) is a B-cell malignancy characterized by the accumulation of clonal plasma cells in the bone marrow. In normal plasma cell development, cells undergo programmed DNA breaks and translocations, a process necessary for generation of a wide repertoire of antigen-specific antibodies....

Descripción completa

Detalles Bibliográficos
Autores principales: Vlummens, Philip, De Veirman, Kim, Menu, Eline, De Bruyne, Elke, Offner, Fritz, Vanderkerken, Karin, Maes, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704229/
https://www.ncbi.nlm.nih.gov/pubmed/31475039
http://dx.doi.org/10.3389/fgene.2019.00740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704229/
https://www.ncbi.nlm.nih.gov/pubmed/31475039
http://dx.doi.org/10.3389/fgene.2019.00740

Ejemplares similares